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CRISPR-Cas systems provide adaptive immunity to bacteria and archaea against viral and plasmid DNA. These systems consist of CRISPR arrays containing short, repetitive sequences interspersed with unique spacer sequences derived from past encounters with foreign genetic elements. Upon re-infection, CRead more
CRISPR-Cas systems provide adaptive immunity to bacteria and archaea against viral and plasmid DNA. These systems consist of CRISPR arrays containing short, repetitive sequences interspersed with unique spacer sequences derived from past encounters with foreign genetic elements. Upon re-infection, CRISPR-associated proteins use these spacer sequences as guide RNAs to target and cleave invading nucleic acids, thereby protecting the host cell from viral infection.
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